Product Description
| Cat Number | ADM-MM108 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Mouse ADAM8 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Pro17-Ser658. |
| Target | ADAM8 |
| Host | Mouse |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | A Disintegrin And Metalloproteinase (ADAM) proteases constitute a family of multifunctional, membrane-bound proteins with traditional sheddase functions. Their protumorigenic potential has been attributed to both, essential (ADAM10 and ADAM17) and 'dispensable' ADAM proteases (ADAM8, 9, 12, 15, and 19). Of specific interest in this review is the ADAM proteinase ADAM8 that has been identified as a significant player in aggressive malignancies including breast, pancreatic, and brain cancer. |
| Molecular Mass | The protein has a predicted MW of 71.7 kDa. The protein migrates to 55-70 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Pro17-Ser658 |
| Appearance | Liquid |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | Q05910 |
| Amino Acid Sequence | Recombinant Mouse ADAM8 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Pro17-Ser658. |
| Storage | Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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