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IDR-1002

SKU: BTL-IB-P-00162 | Brand: Isca Biochemical
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Product Description

Cat Number AM-320
Category Peptide
Pack Size 1 mg
Description Innate defence regulator peptide
Modification C terminal amide
Purity >95% by hplc
Biomarker Target Antibacterials
Sequence Three Letter Code H-Val-Gln-Arg-Trp-Leu-Ile-Val-Trp-Arg-Ile-Arg-Lys-NH2
Molecular Formula C79H130N26O13
Sl Sequence VQRWLIVWRIRK-NH2
Solubility Soluble in water
Appearance Freeze dried solid
Storage Store dry, frozen and in the dark
References Nijnik (2010) Synthetic cationic peptide IDR-1002 provides protection against bacterial infections through chemokine induction and enhanced leukocyte recruitment. J Immunol. 184(5) 2539 PMID: 20107187Wu et al (2017) Mechanisms of the Innate Defense Regulator Peptide-1002 Anti-Inflammatory Activity in a Sterile Inflammation Mouse Model. J Immunol. 199(10) 3592 PMID: 28993516Piyadasa et al (2021) Disrupting Tryptophan in the Central Hydrophobic Region Selectively Mitigates Immunomodulatory Activities of the Innate Defence Regulator Peptide IDR-1002. J Med Chem. 64(10) 6696 PMID: 33974425SebÅ‘k et al (2023) Modulation of the immune response by the host defense peptide IDR-1002 in chicken hepatic cell culture. Sci Rep. 13(1) 14530 PMID: 37666888
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Note The product is for research use only
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