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Human BAFFR/TNFRSF13C Protein (BAF-HM201)

SKU: BTL-KB-P-00264 | Host: Human | Brand: Kactus Bio
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Product Description

Cat Number BAF-HM201
Category Recombinant Protein
Pack Size 100UG
Description Recombinant Human BAFFR/TNFRSF13C Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Ser7-Ala71.
Target BAFFR/TNFRSF13C
Host Human
Purity > 95% as determined by Bis-Tris PAGE
Scientific Background BAFFR is an atypical representative of the TNF-receptor super-family. BAFFR [BAFFR = B cell activating f actor of the TNF-f amily receptor; a.k.a. BR3, Bcmd] expression starts when the immature B cells develop to transitional B cells, which then receive BAFFR-dependent pro-survival signals to rescue them from premature cell death. At protein level, the BAFFR is expressed on the surface of all human peripheral B cell subsets except for plasma cells and for centroblasts located in the dark zone of germinal centers. Its expression is upregulated after the expression of functional B cell antigen receptors (BCR) in response to tonic BCR signaling, which enhances BAFFR expression by immature and transitional B cells
Molecular Mass The protein has a predicted MW of 33.3 kDa. Due to glycosylation, the protein migrates to 40-48 kDa based on Bis-Tris PAGE result.
Sl Sequence Ser7-Ala71
Solubility Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Appearance Lyophilized
Endotoxin Levels Less than 1 EU per μg by the LAL method.
Expression System HEK293
Gene Id Q96RJ3-1
Amino Acid Sequence Recombinant Human BAFFR/TNFRSF13C Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Ser7-Ala71.
Storage -20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Pdf View Document
Note The product is for research use only
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