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Human 4-1BB Ligand/TNFSF9 Trimer Protein (BBL-HM141)

SKU: BTL-KB-P-00289 | Host: Human | Brand: Kactus Bio
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Product Description

Cat Number BBL-HM141
Category Recombinant Protein
Pack Size 100UG
Description Recombinant Human 4-1BB Ligand/TNFSF9 Trimer Protein is expressed from HEK293 with His tag and Flag tag at the N-Terminus.It contains Arg71-Glu254 trimer design.
Target 4-1BB Ligand/TNFSF9
Host Human
Purity > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Scientific Background The 4-1BBL is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. 4-1BB ligand (4-1BBL) is an inducible molecule present on several APC types, including B cells, macrophages and DCs.4-1BB:4-1BBL pathway seems to amplify the existing costimulatory signals, even if the engagement of 4-1BB in the presence of a strong TCR signaling can induce IL-2 production in a CD28-independent manner.
Molecular Mass The protein has a predicted MW of 61.8 kDa same as Bis-Tris PAGE result.
Sl Sequence Arg71-Glu254
Solubility Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Appearance Lyophilized
Endotoxin Levels Less than 1 EU per μg by the LAL method.
Expression System HEK293
Gene Id P41273
Amino Acid Sequence Recombinant Human 4-1BB Ligand/TNFSF9 Trimer Protein is expressed from HEK293 with His tag and Flag tag at the N-Terminus.It contains Arg71-Glu254 trimer design.
Storage -20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Pdf View Document
Note The product is for research use only
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