Human/Mouse BMPR2 Protein (BMP-HM2R2)
SKU: BTL-KB-P-00374 |
Host: Human/Mouse |
Brand: Kactus Bio
Product Description
| Cat Number | BMP-HM2R2 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human/Mouse BMPR2 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Ser27-Thr150. |
| Target | BMPR2 |
| Host | Human/Mouse |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | Bone morphogenetic protein type 2 receptor (BMPR2) is one of the transforming growth factor-β (TGF-β) superfamily receptors, performing diverse roles during embryonic development, vasculogenesis, and osteogenesis. Human BMPR2 consists of 1,038 amino acids, and contains functionally conserved extracellular, transmembrane, kinase, and C-terminal cytoplasmic domains. Bone morphogenetic proteins (BMPs) engage the tetrameric complex, composed of BMPR2 and its corresponding type 1 receptors, which initiates SMAD proteins-mediated signal transduction leading to the expression of target genes implicated in the development or differentiation of the embryo, organs and bones. |
| Molecular Mass | The protein has a predicted MW of 39.84 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Ser27-Thr150 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | Q13873-1(Human) / O35607(Mouse) |
| Amino Acid Sequence | Recombinant Human/Mouse BMPR2 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Ser27-Thr150. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.； -80°C for 3 months after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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