CD54 / ICAM-1(F4-31C2), CF405S conjugate, 0.1mg/mL
SKU: BTL-BIT-B-02657 |
Brand: Biotium
Product Description
| Cat Number | BNC041249-100 |
|---|---|
| Category | Biochemical |
| Pack Size | 1 EA |
| Description | Recognizes an 85-115 kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. ICAM-1 may also be related to progression and metastasis of tumors. |
| Storage | PBS, 0.1% BSA, 0.05% azide |
| Note | The product is for research use only |
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