Plakophilin-1 (PKP1) (10B2), CF405S conjugate, 0.1mg/mL
SKU: BTL-BIT-B-02908 |
Brand: Biotium
Product Description
| Cat Number | BNC041441-500 |
|---|---|
| Category | Biochemical |
| Pack Size | 1 EA |
| Description | This antibody recognizes a protein of 75 kDa, identified as Plakophilin-1. Its epitope maps between aa 1-27 human Plakophilin-1. Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors. |
| Storage | PBS, 0.1% BSA, 0.05% azide |
| Note | The product is for research use only |
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