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CD103 / Integrin alpha E (T-Cell Lymphoma & Hairy Cell Leukemia Marker) (ITGAE/2063), CF405S conjugate, 0.1mg/mL

SKU: BTL-BIT-B-03798 | Brand: Biotium
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Product Description

Cat Number BNC042063-500
Category Biochemical
Pack Size 1 EA
Description CD103 is alpha E integrin, belonging to a small beta-7 integrin subfamily. It is primarily expressed in intraepithelial lymphocytes. Together with beta 7 integrin, it is the cell surface receptor for E-cadherin, where it mediates cell adhesion. CD103 is expressed on more than 95% of intraepithelial CD8 cells and on 40% of mucosa-associated T cells, whereas less than 2% of resting blood lymphocytes are CD103-positive. In several malignant conditions, such as T-cell lymphomas and hairy cell leukemia (HCL), the cells express CD103. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Storage PBS, 0.1% BSA, 0.05% azide
Note The product is for research use only
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