PU.1 (SPI-1) (B-Cell Marker) (PU1/2146), CF405S conjugate, 0.1mg/mL
SKU: BTL-BIT-B-03892 |
Brand: Biotium
Product Description
| Cat Number | BNC042146-500 |
|---|---|
| Category | Biochemical |
| Pack Size | 1 EA |
| Description | PU.1 is a member of the ETS family of transcription factors and is important for normal B-cell development. It is expressed in the myeloid lineage and in immature as well as mature B-lymphocytes, with the exception of plasma cells. PU.1 is expressed in germinal center B-cells and mantle B-cells. Various lymphomas are also positive for this marker. It is essential during early B-cell differentiation. The absence of PU.1 results in total block of B-cell development at the pre-pro stage. PU.1 plays a key role in normal myeloid differentiation, and regulates the expression of immunoglobulin and other genes that are important for B-cell development._x000D_ _x000D_ Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_ _x000D_ |
| Storage | PBS, 0.1% BSA, 0.05% azide |
| Note | The product is for research use only |
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