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Human CA14/Carbonic Anhydrase XIV Protein (CA4-HM214)

SKU: BTL-KB-P-00431 | Host: Human | Brand: Kactus Bio
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Product Description

Cat Number CA4-HM214
Category Recombinant Protein
Pack Size 100UG
Description Recombinant Human CA14/Carbonic Anhydrase XIV Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Ala16-Met290.
Target CA14/Carbonic Anhydrase XIV
Host Human
Purity > 95% as determined by Bis-Tris PAGE
Scientific Background Carbonic anhydrase XIV (CA XIV), a transmembrane protein, highly expressed in the central nervous system, is difficult to recombinantly express and purify in large scale for the measurements of inhibitor binding and drug design. CA XIV belongs to the family of twelve catalytically active CA isoforms in the human body. Disorders in the expression of CA XIV cause serious diseases and CA XIV has been described as a possible drug target for the treatment of epilepsy, some retinopathies, and skin tumors.
Molecular Mass The protein has a predicted MW of 56.76 kDa. Due to glycosylation, the protein migrates to 65-85 kDa based on Bis-Tris PAGE result.
Sl Sequence Ala16-Met290
Appearance Liquid
Endotoxin Levels Less than 0.1 EU per μg by the LAL method.
Expression System HEK293
Gene Id Q9ULX7
Amino Acid Sequence Recombinant Human CA14/Carbonic Anhydrase XIV Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Ala16-Met290.
Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Note The product is for research use only
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