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Human UltraPro Mutant CD19 Protein (CD1-HM129)

SKU: BTL-KB-P-00538 | Host: Human | Brand: Kactus Bio
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Product Description

Cat Number CD1-HM129
Category Recombinant Protein
Pack Size 100UG
Description Recombinant Human UltraPro Mutant CD19 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Pro20-Pro278 with site mutations.
Target CD19
Host Human
Purity > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Scientific Background CD19 is a 95 kDa transmembrane glycoprotein that plays a central role in B cell activation and humoral immune responses. Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens. Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca2 stores.
Molecular Mass The protein has a predicted MW of 29.93 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Bis-Tris PAGE result.
Sl Sequence Pro20-Pro278 with site mutations
Solubility Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Appearance Lyophilized
Endotoxin Levels Less than 0.1 EU per μg by the LAL method.
Expression System HEK293
Gene Id P15391-1
Amino Acid Sequence Recombinant Human UltraPro Mutant CD19 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Pro20-Pro278 with site mutations.
Storage -20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Pdf View Document
Note The product is for research use only
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