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Human CD300LF Protein (CD3-HM2LF)

SKU: BTL-KB-P-00671 | Host: Human | Brand: Kactus Bio
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Product Description

Cat Number CD3-HM2LF
Category Recombinant Protein
Pack Size 100UG
Description Recombinant Human CD300LF Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Thr20-Ser156.
Target CD300LF
Host Human
Purity > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Scientific Background Murine norovirus (MNoV) is an important model of human norovirus (HNoV) and mucosal virus infection more broadly. CD300lf as a proteinaceous receptor for MNoV. Interestingly, its paralogue CD300ld was also sufficient for MNoV infection in vitro. CD300lf is essential for both oral and parenteral MNoV infection and to elicit anti-MNoV humoral responses in vivo. human CD300lf (huCD300lf) is not essential for HNoV infection, nor does huCD300lf inhibit binding of HNoV virus-like particles to glycans.
Molecular Mass The protein has a predicted MW of 42.1 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.
Sl Sequence Thr20-Ser156
Solubility Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Appearance Lyophilized
Endotoxin Levels Less than 1 EU per μg by the LAL method.
Expression System HEK293
Gene Id Q8TDQ1-1
Amino Acid Sequence Recombinant Human CD300LF Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Thr20-Ser156.
Storage -20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Pdf View Document
Note The product is for research use only
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