FITC-Labeled Human Siglec-3/CD33 Protein (CD3-HM433F)
SKU: BTL-KB-P-00678 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | CD3-HM433F |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant FITC-Labeled Human Siglec-3/CD33 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Asp18-His259. |
| Target | Siglec-3/CD33 |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE |
| Scientific Background | CD33 (siglec-3), a well-known target in leukemia therapy, is an inhibitory sialoadhesin expressed in human leukocytes of the myeloid lineage and some lymphoid subsets, including NK cells. CD33 is the smallest siglec member. It preferentially binds to α2-6- and α2-3-sialylated glycans and strongly binds to sialylated ligands on leukemic cell lines. |
| Molecular Mass | The protein has a predicted MW of 29.6 kDa. Due to glycosylation, the protein migrates to 48-58 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Asp18-His259 |
| Appearance | Liquid |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | P20138-1 |
| Amino Acid Sequence | Recombinant FITC-Labeled Human Siglec-3/CD33 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Asp18-His259. |
| Storage | Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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