Cynomolgus CD96/TACTILE Protein (CD9-CM196)
SKU: BTL-KB-P-00822 |
Host: Cynomolgus |
Brand: Kactus Bio
Product Description
| Cat Number | CD9-CM196 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Cynomolgus CD96/TACTILE Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Val22-Gly502. |
| Target | CD96/TACTILE |
| Host | Cynomolgus |
| Purity | > 95% as determined by Bis-Tris PAGE |
| Scientific Background | The receptors CD96 and TIGIT are expressed on the surface of T and natural killer (NK) cells, and recent studies suggest both play important inhibitory roles in immune function. CD96 has been shown to modulate immune cell activity in mice, with Cd96-/- mice displaying hypersensitive NK-cell responses to immune challenge and significant tumor resistance. The counterbalance between the putative inhibitory CD96 and TIGIT receptors and the activating receptor, CD226, offers unique strategies for immuno-oncology drug development. |
| Molecular Mass | The protein has a predicted MW of 54.27 kDa. Due to glycosylation, the protein migrates to 80-130 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Val22-Gly502 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | A0A2K5TWV6 |
| Amino Acid Sequence | Recombinant Cynomolgus CD96/TACTILE Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Val22-Gly502. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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