Human CDH17/Cadherin 17 Domain 1 Protein (CDH-HM31D)
SKU: BTL-KB-P-00927 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | CDH-HM31D |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human CDH17/Cadherin 17 Domain 1 Protein is expressed from HEK293 with mFc (IgG2a) tag at the C-terminus.It contains Gln23-Gln128. |
| Target | CDH17/Cadherin 17 |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. |
| Molecular Mass | The protein has a predicted MW of 38.29 kDa. Due to glycosylation, the protein migrates to 43-53 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Gln23-Gln128 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | Q12864 |
| Amino Acid Sequence | Recombinant Human CDH17/Cadherin 17 Domain 1 Protein is expressed from HEK293 with mFc (IgG2a) tag at the C-terminus.It contains Gln23-Gln128. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.； -80°C for 3 months after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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