Biotinylated Human CDH17/Cadherin 17 Domain 5-7 Protein (CDH-HM4D4B)
SKU: BTL-KB-P-00946 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | CDH-HM4D4B |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Biotinylated Human CDH17/Cadherin 17 Domain 5-7 Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Glu450-Gly777. |
| Target | CDH17/Cadherin 17 |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE |
| Scientific Background | Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. |
| Molecular Mass | The protein has a predicted MW of 38.6 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Tris-Bis PAGE result. |
| Sl Sequence | Glu450-Gly777 |
| Appearance | Liquid |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | Q12864 |
| Amino Acid Sequence | Recombinant Biotinylated Human CDH17/Cadherin 17 Domain 5-7 Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Glu450-Gly777. |
| Storage | Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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