Mouse CDH17/Cadherin 17 Protein (CDH-MM117)
SKU: BTL-KB-P-00951 |
Host: Mouse |
Brand: Kactus Bio
Product Description
| Cat Number | CDH-MM117 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Mouse CDH17/Cadherin 17 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe26-Met786. |
| Target | CDH17/Cadherin 17 |
| Host | Mouse |
| Purity | > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC |
| Scientific Background | Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. |
| Molecular Mass | The protein has a predicted MW of 85.4 kDa. Due to glycosylation, the protein migrates to 90-115 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Phe26-Met786 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | Q9R100 |
| Amino Acid Sequence | Recombinant Mouse CDH17/Cadherin 17 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe26-Met786. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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