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Human/Cynomolgus/Rhesus macaque CD40 Ligand/TNFSF5 Protein (CDL-HE14L)

SKU: BTL-KB-P-00956 | Host: Human/Cynomolgus/Rhesus macaque | Brand: Kactus Bio
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Product Description

Cat Number CDL-HE14L
Category Recombinant Protein
Pack Size 100UG
Description Recombinant Human/Cynomolgus/Rhesus macaque CD40 Ligand/TNFSF5 Protein is expressed from E.coli with His tag at the C-terminus.It contains Gln114-Leu261.
Target CD40 Ligand/TNFSF5
Host Human/Cynomolgus/Rhesus macaque
Purity > 95% as determined by Bis-Tris PAGE
Scientific Background CD40 ligand or CD40L, also called CD154,  is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, α5β1 integrin and αIIbβ3. CD154 acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells.
Molecular Mass The protein has a predicted MW of 17.15 kDa same as Bis-Tris PAGE result.
Sl Sequence Gln114-Leu261
Appearance Liquid
Endotoxin Levels Less than 1 EU per μg by the LAL method.
Expression System E.coli
Gene Id P29965(Human) /G7Q1T4(Cynomolgus) /P63304(Rhesus macaque)
Amino Acid Sequence Recombinant Human/Cynomolgus/Rhesus macaque CD40 Ligand/TNFSF5 Protein is expressed from E.coli with His tag at the C-terminus.It contains Gln114-Leu261.
Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Pdf View Document
Note The product is for research use only
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