Human Complement Factor D/CFD Protein (CFD-HM201)
SKU: BTL-KB-P-00988 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | CFD-HM201 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human Complement Factor D/CFD Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Ile26-Ala253. |
| Target | Complement Factor D/CFD |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE |
| Scientific Background | Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium. |
| Molecular Mass | The protein has a predicted MW of 51.2 kDa. Due to glycosylation, the protein migrates to 52-60 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Ile26-Ala253 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | P00746-1 |
| Amino Acid Sequence | Recombinant Human Complement Factor D/CFD Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Ile26-Ala253. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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