Product Description
Cat Number | CK-040 |
---|---|
Category | Peptide |
Pack Size | 1 mg |
Description | Competes with CXCL8 for GAG binding |
Modification | None |
Purity | >95% by hplc |
Biomarker Target | Chemokine receptors |
Sequence Three Letter Code | H-Lys-Lys-Lys-Gln-Lys-Asn-Gly-Lys-Lys-His-Gln-Lys-Lys-Lys-Val-Leu-Lys-Val-Arg-Lys-Ser-Gln-Arg-Ser-Arg-Gln-Lys-Lys-Thr-Thr-OH |
Molecular Formula | C158H295N59O40 |
Sl Sequence | KKKQKNGKKHQKKKVLKVRKSQRSRQKKTT |
Solubility | Soluble in water |
Appearance | Freexe dried solid |
Storage | Store dry, frozen and in the dark |
References |
Vanheule et al (2015) The Positively Charged COOH-terminal Glycosaminoglycan-binding CXCL9(74-103) Peptide Inhibits CXCL8-induced Neutrophil Extravasation and Monosodium Urate Crystal-induced Gout in Mice. J Biol Chem. 290(35) 21292 PMID: 26183778Boff (2018) The chemokine fragment CXCL9(74-103) diminishes neutrophil recruitment and joint inflammation in antigen-induced arthritis. J Leukoc Biol. 104(2) 413 PMID: 29733455De Zutter et al (2021) The Chemokine-Based Peptide, CXCL9(74-103), Inhibits Angiogenesis by Blocking Heparan Sulfate Proteoglycan-Mediated Signaling of Multiple Endothelial Growth Factors. Cancers 13(20) 5090 PMID: 34680238 Related areasAll peptides >All chemokine receptor modulators >All immunology research categories > |
Note | The product is for research use only |
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