Human CLEC4M/CD299 Protein (CLE-HM04E)
SKU: BTL-KB-P-01022 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | CLE-HM04E |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human CLEC4M/CD299 Protein is expressed from HEK293 without tag.It contains Gln71-Glu399. |
| Target | CLEC4M/CD299 |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | CLEC4M, also known as DC-SIGNR, L-SIGN or CD209L, is a Ca2+-dependent C-type lectin. CLEC4M and its homologue DC-SIGN are encoded by the closely related lectin gene cluster on chromosome 19p13.3. higher expression of CLEC4M is associated with poor clinical prognosis in lung cancer patients and enhances the resistance of NSCLC cells to cisplatin. Inhibition of CLEC4M expression significantly increased cisplatin sensitivity, suggesting potential clinical significance for targeting CLEC4M in overcoming cisplatin resistance. |
| Molecular Mass | The protein has a predicted MW of 37.72 kDa. Due to glycosylation, the protein migrates to 38-50 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Gln71-Glu399 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | Q9H2X3-1 |
| Amino Acid Sequence | Recombinant Human CLEC4M/CD299 Protein is expressed from HEK293 without tag.It contains Gln71-Glu399. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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