Human MDL-1/CLEC5A Protein (CLE-HM25A)
SKU: BTL-KB-P-01035 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | CLE-HM25A |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human MDL-1/CLEC5A Protein is expressed from HEK293 with hFc (IgG1) tag at the N-Terminus.It contains Tyr26-Lys188. |
| Target | MDL-1/CLEC5A |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | In C. elegans, increased lifespan in daf-2 insulin/IGF-1 receptor mutants is accompanied by up-regulation of the MDL-1 Mad basic helix-loop-helix leucine zipper transcription factor.MDL-1, like its mammalian orthologs, is an inhibitor of cell proliferation and growth that slows progression of an age-related pathology in C. elegans (uterine tumors). In addition, intestine-limited rescue of mdl-1 increased lifespan but not to wild type levels. Thus, mdl-1 likely acts both in the intestine and the germline to influence age-related mortality. |
| Molecular Mass | The protein has a predicted MW of 46 kDa. Due to glycosylation, the protein migrates to 63-70 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Tyr26-Lys188 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | Q9NY25-1 |
| Amino Acid Sequence | Recombinant Human MDL-1/CLEC5A Protein is expressed from HEK293 with hFc (IgG1) tag at the N-Terminus.It contains Tyr26-Lys188. |
| Storage | -20 to -80°C for 24 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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