Mouse Clusterin Protein (CLN-MM101)
SKU: BTL-KB-P-01058 |
Host: Mouse |
Brand: Kactus Bio
Product Description
| Cat Number | CLN-MM101 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Mouse Clusterin Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu22-Glu448. |
| Target | Clusterin |
| Host | Mouse |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | Clusterin (CLU) is a stress-activated, ATP-independent molecular chaperone, normally secreted from cells, that is up-regulated in Alzheimer disease and in many cancers. It plays important roles in protein homeostasis/proteostasis, inhibition of cell death pathways, and modulation of pro-survival signalling and transcriptional networks. Changes in the CLU gene locus are highly associated with Alzheimer disease, and many therapy-resistant cancers over-express CLU. |
| Molecular Mass | The protein has a predicted MW of 50.4 kDa. Due to autocatalytic cleavage, the protein migrates to 35-40 kDa and 43-50 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Glu22-Glu448 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | Q06890 |
| Amino Acid Sequence | Recombinant Mouse Clusterin Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu22-Glu448. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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