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α-helical CRF (9-41)

SKU: BTL-IB-P-00169 | Brand: Isca Biochemical

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Product Description

Cat Number	CR-010
Category	Peptide
Pack Size	1 mg
Description	CRF antagonist
Modification	C-terminal amide
Purity	>95% by hplc
Biomarker Target	Corticotropin releasing factor receptors
Sequence Three Letter Code	H-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Met-Leu-Glu-Met-Ala-Lys-Ala-Glu-Gln-Glu-Ala-Glu-Gln-Ala-Ala-Leu-Asn-Arg-Leu-Leu-Leu-Glu-Glu-Ala-NH2
Molecular Formula	C166H274N46O53S2
Sl Sequence	DLTFHLLREMLEMAKAEQEAEQAALNRLLLEEA-NH2
Solubility	Soluble to 1 mg/ml in 0.1% TFA
Appearance	Freeze dried solid
Storage	Store dry, frozen and in the dark
References	Swerdlow et al (1989) Potentiation of acoustic startle by corticotropin-releasing factor (CRF) and by fear are both reversed by α-helical CRF (9-41). Neuropsychopharmacology 2 285 PMID: 2610824SkÃ³rzewska et al (2009). The effect of CRF and α-helical CRF(9-41) on rat fear responses and amino acids release in the central nucleus of the amygdala. Neuropharmacology 57(2) 148 PMID: 19477189Smedh et al (2019) Pretreatment with a CRF antagonist amplifies feeding inhibition induced by fourth ventricular cocaine- and amphetamine-regulated transcript peptide. BMC Neurosci 20 11 PMID: 30885137 Related areas_x000D_ All peptides >All corticotropin releasing factor receptor modulators >All endocrinology categories >All neuroscience categories >All appetite regulation categories >
Note	The product is for research use only

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