Cynomolgus CRTAM Protein, Ultra Low Endotoxin (CRM-CM101-UL)
SKU: BTL-KB-P-01112 |
Host: Cynomolgus |
Brand: Kactus Bio
Product Description
| Cat Number | CRM-CM101-UL |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Cynomolgus CRTAM Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser18-Gly287. |
| Target | CRTAM |
| Host | Cynomolgus |
| Purity | > 95% as determined by Bis-Tris PAGE |
| Scientific Background | Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of IL-17, IL-22, and IFNγ by murine CD4 T cells, and it plays a role in optimal CD8 T and NK cell cytotoxicity. CRTAM promotes the pro-inflammatory cytokine profile; therefore, it may take part in the immunopathology of autoimmune diseases such as diabetes type 1 or colitis. |
| Molecular Mass | The protein has a predicted MW of 30.80 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Ser18-Gly287 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 0.01 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | XP_005580021.1 |
| Amino Acid Sequence | Recombinant Cynomolgus CRTAM Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser18-Gly287. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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