Cynomolgus M-CSF/CSF-1 Protein (CSF-CM101)
SKU: BTL-KB-P-01121 |
Host: Cynomolgus |
Brand: Kactus Bio
Product Description
| Cat Number | CSF-CM101 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Cynomolgus M-CSF/CSF-1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu33-Leu255. |
| Target | M-CSF/CSF-1 |
| Host | Cynomolgus |
| Purity | > 95% as determined by Bis-Tris PAGE |
| Scientific Background | CSF-1, also known as M-CSF , is a four alpha -helical-bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation. CSF-1 is also essential for the survival and proliferation of osteoclast progenitors.CSF-1 is cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. This mutation leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand. |
| Molecular Mass | The protein has a predicted MW of 26.26 kDa. Due to glycosylation, the protein migrates to 45-55 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Glu33-Leu255 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | XP_045221641.1 |
| Amino Acid Sequence | Recombinant Cynomolgus M-CSF/CSF-1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu33-Leu255. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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