Mouse CTLA-4/CD152 Protein (CTL-MM141)
SKU: BTL-KB-P-01149 |
Host: Mouse |
Brand: Kactus Bio
Product Description
| Cat Number | CTL-MM141 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Mouse CTLA-4/CD152 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Glu36-Asp161. |
| Target | CTLA-4/CD152 |
| Host | Mouse |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), also known as CD152, is a protein receptor that, functioning as an immune checkpoint, downregulates immune responses.CTLA4 is constitutively expressed in regulatory T cells but only upregulated in conventional T cells after activation – a phenomenon which is particularly notable in cancers. It acts as an "off" switch when bound to CD80 or CD86 on the surface of antigen-presenting cells. |
| Molecular Mass | The protein has a predicted MW of 15.47 kDa. Due to glycosylation, the protein migrates to 28-38 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Glu36-Asp161 |
| Appearance | Liquid |
| Endotoxin Levels | Less than 0.1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | P09793 |
| Amino Acid Sequence | Recombinant Mouse CTLA-4/CD152 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Glu36-Asp161. |
| Storage | Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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