Product Description
| Cat Number | CXC-HM1R5 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human CXCR5 VLP is expressed from HEK293.It contains Met1-Phe372 (It may have cross reaction with anti-His antibody). |
| Target | CXCR5 |
| Host | Human |
| Purity | > 95% as determined by HPLC |
| Scientific Background | CXCR5 is a serpentine receptor implicated in cell migration in lymphocytes and differentiation in leukocytes. It causes MAPK pathway activation and has known membrane partners for signaling. CXCR5 is also expressed in HL-60 cells, a human acute myeloid leukemia line, following treatment with all-trans retinoic acid, which induces differentiation toward a neutrophil-like state. CXCR5 is necessary for this process; differentiation was crippled in CXCR5 knockout cells and enhanced in cells ectopically expressing it. |
| Molecular Mass | The protein has a predicted MW of 54.90 kDa. |
| Sl Sequence | Met1-Phe372 |
| Appearance | Liquid |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | P32302-1 |
| Amino Acid Sequence | Recombinant Human CXCR5 VLP is expressed from HEK293.It contains Met1-Phe372 (It may have cross reaction with anti-His antibody). |
| Storage | Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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