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Cibinetide

SKU: BTL-IB-P-00089 | Brand: Isca Biochemical

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Product Description

Cat Number	CY-070
Category	Peptide
Pack Size	1 mg
Description	Erythropoietin/CD131 heteroreceptor agonist
Modification	X is pyroglutamic acid
Purity	>95% by hplc
Biomarker Target	Cytokine receptors
Sequence Three Letter Code	Glp-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser-OH (Glp is pyroglutamic acid)
Molecular Formula	C51H84N16O21
Sl Sequence	XEQLERALNSS
Solubility	> 50 mg per ml in water
Appearance	Freeze dried solid
Storage	Store dry, frozen and in the dark
References	Brines et al (2008) Nonerythropoietic, tissue-protective peptides derived from the tertiary structure of erythropoietin. Proc Natl Acad Sci U S A 105(31) 10925 PMID: 18676614Swartjes et al (2014) ARA 290, a peptide derived from the tertiary structure of erythropoietin, produces long-term relief of neuropathic pain coupled with suppression of the spinal microglia response. Mol Pain 10 13 PMID: 24529189Zhang and Zhang (2016) ARA 290 relieves pathophysiological pain by targeting TRPV1 channel: Integration between immune system and nociception. Peptides 76 73 PMID: 26774587Ghassemi-Barghi et al (2023) Mechanistic Approach for Protective Effect of ARA290, a Specific Ligand for the Erythropoietin/CD131 Heteroreceptor, against Cisplatin-Induced Nephrotoxicity, the Involvement of Apoptosis and Inflammation Pathways. Inflammation 46(1)342 PMID: 36085231Guide to Pharmacology - Cibinetide Related areas All peptides >All cytokine receptor modulators >All immunology research categories >All pain research categories >
Note	The product is for research use only

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