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Biotinylated Human DDR1 Protein (DDR-HM4R1B)

SKU: BTL-KB-P-01187 | Host: Human | Brand: Kactus Bio
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Product Description

Cat Number DDR-HM4R1B
Category Recombinant Protein
Pack Size 100UG
Description Recombinant Biotinylated Human DDR1 Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Asp21-Ala417.
Target DDR1
Host Human
Purity > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Scientific Background Discoidin domain receptor1 (DDR1) is a collagen activated receptor tyrosine kinase and an attractive anti-fibrotic target. Its expression is mainly limited to epithelial cells located in several organs including skin, kidney, liver and lung. DDR1's biology is elusive, with unknown downstream activation pathways; however, it may act as a mediator of the stromal-epithelial interaction, potentially controlling the activation state of the resident quiescent fibroblasts.
Molecular Mass The protein has a predicted MW of 46.93 kDa. Due to glycosylation, the protein migrates to 60-75 kDa based on Bis-Tris PAGE result.
Sl Sequence Asp21-Ala417
Solubility Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Appearance Lyophilized
Endotoxin Levels Less than 1 EU per μg by the LAL method.
Expression System HEK293
Gene Id Q08345-1
Amino Acid Sequence Recombinant Biotinylated Human DDR1 Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Asp21-Ala417.
Storage -20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Pdf View Document
Note The product is for research use only
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