Cynomolgus DR6/TNFRSF21 Protein (DR6-CM101)
SKU: BTL-KB-P-01253 |
Host: Cynomolgus |
Brand: Kactus Bio
Product Description
| Cat Number | DR6-CM101 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Cynomolgus DR6/TNFRSF21 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln42-His349. |
| Target | DR6/TNFRSF21 |
| Host | Cynomolgus |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | beta-amyloid precursor protein (APP) and death receptor 6 (DR6, also known as TNFRSF21) activate a widespread caspase-dependent self-destruction program. DR6 is broadly expressed by developing neurons, and is required for normal cell body death and axonal pruning both in vivo and after trophic-factor deprivation in vitro.DR6 is activated locally by an inactive surface ligand(s) that is released in an active form after trophic-factor deprivation. |
| Molecular Mass | The protein has a predicted MW of 34.50 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Gln42-His349 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | A0A2K5VIJ8 |
| Amino Acid Sequence | Recombinant Cynomolgus DR6/TNFRSF21 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln42-His349. |
| Storage | -20 to -80°C for 24 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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