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IRL 1620

SKU: BTL-IB-P-00167 | Brand: Isca Biochemical

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Product Description

Cat Number	ER-020
Category	Peptide
Pack Size	1 mg
Description	Highly selective endothelin B receptor agonist
Modification	Asp-1 is succinylated
Purity	>95% by hplc
Biomarker Target	Endothelin receptors
Sequence Three Letter Code	Suc-Asp-Glu-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-OH
Molecular Formula	C86H117N17O27
Sl Sequence	Suc-DEEAVYFAHLDIIW
Solubility	Soluble to 0.70 mg/ml in water
Appearance	Freeze dried solid
Storage	Store dry, frozen and in the dark
References	Takai et al (1992) A potent and specific agonist, Suc-[Glu9,Ala11,15]-endothelin-1(8-21), IRL 1620, for the ETB receptor. Biochem.Biophys.Res.Commun. 184 953 PMID: 1315540Cemazar et al (2005)The endothelin B (ETB) receptor agonist IRL 1620 is highly vasoconstrictive in two syngeneic rat tumour lines: potential for selective tumour blood flow modification. Br J Cancer 93 98 PMID: 15970923Cifuentes et al (2018) Neuroprotective Effect of IRL-1620, an Endothelin B Receptor Agonist, on a Pediatric Rat Model of Middle Cerebral Artery. Frontiers in Pediatrics 6 310 PMID: 30406063Ranjan et al (2020) Sovateltide (IRL-1620) activates neuronal differentiation and prevents mitochondrial dysfunction in adult mammalian brains following stroke. Sci Rep. 10(1) 12737 PMID: 32728189 Related areas All peptides >All endothelin receptor modulators >All neuroscience research categories >All endocrinology research categories >
Note	The product is for research use only

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