Biotinylated Human Fc gamma RIIA/CD32a (R167) Protein (FCR-HM42AB)
SKU: BTL-KB-P-01404 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | FCR-HM42AB |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Biotinylated Human Fc gamma RIIA/CD32a (R167) Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gln34-Ile218(R167). |
| Target | Fc gamma RIIA/CD32a |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | The Fc gamma Rs have been divided into three classes based on close relationships in their extracellular domains; these groups are designated Fc gamma RI (also known as CD64), Fc gamma RII (CD32), and Fc gamma RIII (CD16). Each group may be encoded by multiple genes and exist in different isoforms depending on species and cell type. The CD64 proteins are high affinity receptors (~10e-8-10e-9 M) capable of binding monomeric IgG, whereas the CD16 and CD32 proteins bind IgG with lower affinities (~10e-6-10e-7 M) only recognizing IgG aggregates surrounding multivalent antigens. |
| Molecular Mass | The protein has a predicted MW of 23.4 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Gln34-Ile218(R167) |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | P12318-1 |
| Amino Acid Sequence | Recombinant Biotinylated Human Fc gamma RIIA/CD32a (R167) Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gln34-Ile218(R167). |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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