Human FGFR2 beta (IIIb) Domain Protein (FGF-HM2BD)
SKU: BTL-KB-P-01433 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | FGF-HM2BD |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human FGFR2 beta (IIIb) Domain Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Pro253-Glu378. |
| Target | FGFR2 beta (IIIb) |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs. A frequent splicing event involving FGF R1 and 2 results in receptors containing all three Ig domains, referred to as the alpha isoform, or only IgII and IgIII, referred to as the beta isoform. |
| Molecular Mass | The protein has a predicted MW of 40.5 kDa. Due to glycosylation, the protein migrates to 60-68 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Pro253-Glu378 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | P21802-3 |
| Amino Acid Sequence | Recombinant Human FGFR2 beta (IIIb) Domain Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Pro253-Glu378. |
| Storage | -20 to -80°C for 24 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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