Mouse GITR Ligand/TNFSF18 Protein (FSF-MM218)
SKU: BTL-KB-P-01550 |
Host: Mouse |
Brand: Kactus Bio
Product Description
| Cat Number | FSF-MM218 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Mouse GITR Ligand/TNFSF18 Protein is expressed from HEK293 with hFc (IgG1) tag at the N-Terminus.It contains Thr47-Ser173. |
| Target | GITR Ligand/TNFSF18 |
| Host | Mouse |
| Purity | > 95% as determined by Bis-Tris PAGE |
| Scientific Background | Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the important role that GITR plays in regulating immune functions, agonistic stimulation of GITR is a promising therapeutic concept. |
| Molecular Mass | The protein has a predicted MW of 41.8 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Thr47-Ser173 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | Q7TS55 |
| Amino Acid Sequence | Recombinant Mouse GITR Ligand/TNFSF18 Protein is expressed from HEK293 with hFc (IgG1) tag at the N-Terminus.It contains Thr47-Ser173. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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