Biotinylated Human GDF15 Protein (Primary Amine Labeling) (GDF-HM215B)
SKU: BTL-KB-P-01631 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | GDF-HM215B |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Biotinylated Human GDF15 Protein (Primary Amine Labeling) is expressed from HEK293 with hFc (IgG1) tag at the N-Terminus.It contains Ala197-Ile308. |
| Target | GDF15 |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. |
| Molecular Mass | The protein has a predicted MW of 37.9 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Ala197-Ile308 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | Q99988 |
| Amino Acid Sequence | Recombinant Biotinylated Human GDF15 Protein (Primary Amine Labeling) is expressed from HEK293 with hFc (IgG1) tag at the N-Terminus.It contains Ala197-Ile308. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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