Biotinylated Human Latent GDF-8 Protein (GDF-HM418B)
SKU: BTL-KB-P-01635 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | GDF-HM418B |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Biotinylated Human Latent GDF-8 Protein is expressed from HEK293 with His tag and Avi Tag at the N-terminus.It contains Asn24-Ser375. |
| Target | GDF-8 |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC |
| Scientific Background | Growth/differentiation factor 8 (GDF8), or myostatin, negatively regulates muscle mass. GDF8 is held in a latent state through interactions with its N-terminal prodomain. GDF8, like numerous TGF-β family members, is a disulfidelinked dimer that is synthesized as a precursor protein which requires cleavage by a furin-like protease to yield an N-terminal prodomain and a C-terminal mature, signaling domain. |
| Molecular Mass | The protein has a predicted MW of 43 kDa. Due to glycosylation, the protein migrates to 13-15 kDa and 35-40 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Asn24-Ser375 |
| Appearance | Liquid |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | O14793 |
| Amino Acid Sequence | Recombinant Biotinylated Human Latent GDF-8 Protein is expressed from HEK293 with His tag and Avi Tag at the N-terminus.It contains Asn24-Ser375. |
| Storage | Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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