Product Description
| Cat Number | GIP-MM201 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Mouse GIP Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Glu22-Gln85. |
| Target | GIP |
| Host | Mouse |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | The potential application of glucose-dependent insulinotropic polypeptide (gastric inhibitory polypeptide, GIP) in the management of obesity and type 2 diabetes has been controversial. Initial interest in the therapeutic use of GIP was dampened by evidence that its insulinotropic activity was reduced in type 2 diabetes and by reports that it increased glucagon secretion and adipose deposition in non-diabetic individuals. |
| Molecular Mass | The protein has a predicted MW of 34.3 kDa. Due to glycosylation, the protein migrates to 40-45 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Glu22-Gln85 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | P48756 |
| Amino Acid Sequence | Recombinant Mouse GIP Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Glu22-Gln85. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |

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