Human GM-CSF R alpha Protein (GSF-HM2RA)
SKU: BTL-KB-P-01727 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | GSF-HM2RA |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human GM-CSF R alpha Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Glu23-Gly320. |
| Target | GM-CSF R alpha |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | The receptor for granulocyte-macrophage colony-stimulating factor (GM-CSF) is composed of an alpha and beta subunit, which together form the high-affinity receptor. The alpha subunit by itself binds ligand at low affinity, whereas the isolated beta subunit does not bind GM-CSF. It is generally believed that the high-affinity receptor is responsible for the multiple functions of GM-CSF and that the isolated alpha subunit (GMR alpha) does not transduce a signal. |
| Molecular Mass | The protein has a predicted MW of 63.5 kDa. Due to glycosylation, the protein migrates to 80-100 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Glu23-Gly320 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | P15509-1 |
| Amino Acid Sequence | Recombinant Human GM-CSF R alpha Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Glu23-Gly320. |
| Storage | -20 to -80°C for 24 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |

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