Biotinylated Human HMGB1 Protein (Primary Amine Labeling) (HMG-HM1B1B)
SKU: BTL-KB-P-01788 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | HMG-HM1B1B |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Biotinylated Human HMGB1 Protein (Primary Amine Labeling) is expressed from HEK293 with His tag at the C-Terminus.It contains Met1-Glu215. |
| Target | HMGB1 |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | High-mobility group box 1 (HMGB1) is a ubiquitous nuclear protein that promotes inflammation when released extracellularly after cellular activation, stress, damage or death. HMGB1 operates as one of the most intriguing molecules in inflammatory disorders via recently elucidated signal and molecular transport mechanisms. Treatments based on antagonists specifically targeting extracellular HMGB1 have generated encouraging results in a wide number of experimental models of infectious and sterile inflammation. |
| Molecular Mass | The protein has a predicted MW of 26 kDa. Due to glycosylation, the protein migrates to 32-36 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Met1-Glu215 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per ug by the LAL method. |
| Expression System | HEK293 |
| Gene Id | P09429-1 |
| Amino Acid Sequence | Recombinant Biotinylated Human HMGB1 Protein (Primary Amine Labeling) is expressed from HEK293 with His tag at the C-Terminus.It contains Met1-Glu215. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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