Biotinylated Mouse IL-17A&F Protein (IAF-MM117B)
SKU: BTL-KB-P-01810 |
Host: Mouse |
Brand: Kactus Bio
Product Description
| Cat Number | IAF-MM117B |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Biotinylated Mouse IL-17A&F Protein is expressed as a heterodimer of IL-17A and IL-17F by co-expression in HEK293. Subunit IL-17A is fused with a Strep II tag at the N-terminus and subunit IL-17F is fused with a His tag and a Avi tag at the C-terminus.It contains Ala26-Ala158 (IL-17A) and Arg29-Ala161 (IL-17F). |
| Target | IL-17A&F |
| Host | Mouse |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | Interleukin‑17A (IL‑17A), also known as CTLA‑8, is a 15‑20 kDa glycosylated cytokine that plays an important role in anti‑microbial and chronic inflammation. The six IL‑17 cytokines (IL‑17A‑F) are encoded by separate genes but adopt a conserved cystine knot fold.IL-17A is a ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines. |
| Molecular Mass | The protein has a predicted MW of 16.01 kDa (IL-17A) and 15.98 kDa (IL-17F). Due to glycosylation, the protein migrates to 17-23 kDa and 30-35 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Ala26-Ala158(IL-17A) & Arg29-Ala161(IL-17F) |
| Appearance | Liquid |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | Q62386(IL-17A)&Q7TNI7-1(IL-17F) |
| Amino Acid Sequence | Recombinant Biotinylated Mouse IL-17A&F Protein is expressed as a heterodimer of IL-17A and IL-17F by co-expression in HEK293. Subunit IL-17A is fused with a Strep II tag at the N-terminus and subunit IL-17F is fused with a His tag and a Avi tag at the C-terminus.It contains Ala26-Ala158 (IL-17A) and Arg29-Ala161 (IL-17F). |
| Storage | Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
Share Item: