Human IFN alpha 1 Protein (IFN-HM2A1)
SKU: BTL-KB-P-01837 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | IFN-HM2A1 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human IFN alpha 1 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Cys24-Glu189. |
| Target | IFN alpha 1 |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | IFN-α, a cytokine expressed in human islets from individuals affected by type 1 diabetes, plays a key role in the pathogenesis of diabetes by upregulating inflammation, endoplasmic reticulum (ER) stress and MHC class I overexpression, three hallmarks of islet histology in early type 1 diabetes. |
| Molecular Mass | The protein has a predicted MW of 46.14 kDa. Due to glycosylation, the protein migrates to 48-55 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Cys24-Glu189 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | P01562 |
| Amino Acid Sequence | Recombinant Human IFN alpha 1 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Cys24-Glu189. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |

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