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Human IFN alpha 1 Protein (IFN-HM2A1)

SKU: BTL-KB-P-01837 | Host: Human | Brand: Kactus Bio
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Product Description

Cat Number IFN-HM2A1
Category Recombinant Protein
Pack Size 100UG
Description Recombinant Human IFN alpha 1 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Cys24-Glu189.
Target IFN alpha 1
Host Human
Purity > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Scientific Background IFN-α, a cytokine expressed in human islets from individuals affected by type 1 diabetes, plays a key role in the pathogenesis of diabetes by upregulating inflammation, endoplasmic reticulum (ER) stress and MHC class I overexpression, three hallmarks of islet histology in early type 1 diabetes.
Molecular Mass The protein has a predicted MW of 46.14 kDa. Due to glycosylation, the protein migrates to 48-55 kDa based on Bis-Tris PAGE result.
Sl Sequence Cys24-Glu189
Solubility Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Appearance Lyophilized
Endotoxin Levels Less than 1 EU per μg by the LAL method.
Expression System HEK293
Gene Id P01562
Amino Acid Sequence Recombinant Human IFN alpha 1 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Cys24-Glu189.
Storage -20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Pdf View Document
Note The product is for research use only
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