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ATN 161

SKU: BTL-IB-P-00050 | Brand: Isca Biochemical

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Product Description

Cat Number	IG-040
Category	Peptide
Pack Size	5 mg
Description	α5β1 integrin receptor antagonist
Modification	N-terminal acetyl, C-terminal amide
Purity	>95% by hplc
Biomarker Target	Integrin receptors
Sequence Three Letter Code	Ac-Pro-His-Ser-Cys-Asn-NH2
Molecular Formula	C23H35N9O8S
Sl Sequence	Ac-PHSCN-NH2
Solubility	Soluble to 2 mg/ml in water
Appearance	Freeze dried solid
Storage	Store dry, frozen and in the dark
References	Livant et al (2000) Anti-invasive, antitumorigenic, and antimetastatic activities of the PHSCN sequence in prostate carcinoma. Cancer Res. 60 309 PMID: 10667582Khalili et al (2006) A non-RGD-based integrin binding peptide (ATN-161) blocks breast cancer growth and metastasis in vivo. Mol.Cancer Ther. 5 2271 PMID: 16985061DoÃ±ate (2008) Pharmacology of the novel antiangiogenic peptide ATN-161 (Ac-PHSCN-NH2): observation of a U-shaped dose-response curve in several preclinical models of angiogenesis and tumor growth. Clin Cancer Res. 14(7) 2137 PMID: 18381955 Related areas_x000D_ All peptides >All integrin receptor modulators >All immunology research categories >All cancer research categories >
Note	The product is for research use only

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