Human IgG1 Fc Protein, Ultra Low Endotoxin (IGG-HM001-UL)
SKU: BTL-KB-P-01890 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | IGG-HM001-UL |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human IgG1 Fc is expressed from HEK293 without tag.It contains Asp104-Lys330. |
| Target | IgG1 Fc |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR) on phagocytic cells with high affinity. Fc fragment is demonstrated to mediate phagocytosis, trigger inflammation, and target Ig to particular tissues.IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases. |
| Molecular Mass | The protein has a predicted MW of 25.5 kDa. Due to glycosylation, the protein migrates to 31-33 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Asp104-Lys330 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 0.001 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | P01857-1 |
| Amino Acid Sequence | Recombinant Human IgG1 Fc is expressed from HEK293 without tag.It contains Asp104-Lys330. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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