Cynomolgus IL-12 Protein (IL1-CM112)
SKU: BTL-KB-P-01906 |
Host: Cynomolgus |
Brand: Kactus Bio
Product Description
| Cat Number | IL1-CM112 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Cynomolgus IL-12 Protein is expressed from HEK293 with His tag at the C-Terminus of IL-12A.It contains Arg57-Ser253 (IL-12A) and Ile23-Ser328 (IL-12B). |
| Target | IL-12 |
| Host | Cynomolgus |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | Interleukin 12 (IL-12) is a pleiotropic cytokine that plays an essential role in Th1-type immune response against cancer, a condition where cells in a particular part of the body grow and reproduce uncontrollably. |
| Molecular Mass | The protein has a predicted MW of 34.76 kDa (IL-12B) and 23.64 kDa (IL-12A). Due to glycosylation, the protein migrates to 45-48 kDa (IL-12B) and 38-44 kDa (IL-12A) based on Bis-Tris PAGE result. |
| Sl Sequence | Ile23-Ser328(IL-12B) & Arg57-Ser253(IL-12A) |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | G7P6S2(IL-12B)&XP_005546300.2(IL-12A) |
| Amino Acid Sequence | Recombinant Cynomolgus IL-12 Protein is expressed from HEK293 with His tag at the C-Terminus of IL-12A.It contains Arg57-Ser253 (IL-12A) and Ile23-Ser328 (IL-12B). |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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