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Cynomolgus IL-10 R alpha Protein (IL1-CM1RA)

SKU: BTL-KB-P-01911 | Host: Cynomolgus | Brand: Kactus Bio
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Product Description

Cat Number IL1-CM1RA
Category Recombinant Protein
Pack Size 100UG
Description Recombinant Cynomolgus IL-10 R alpha Protein is expressed from HEK293 with His tag at the C-Terminus.It contains His22-Asn233.
Target IL-10 R alpha
Host Cynomolgus
Purity > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Scientific Background The interleukin-10 receptor alpha (IL10RA) gene codes for the alpha chain of the IL-10 receptor which binds the cytokine IL-10. IL-10 is an anti-inflammatory cytokine with immunoregulatory function during the pathogenesis of many inflammatory disorders in livestock, including Johne's disease (JD). JD is a chronic enteritis in cattle caused by Mycobacterium avium subsp. paratuberculosis (MAP) and is responsible for significant economic losses to the dairy industry. Several candidate genes including IL10RA have been found to be associated with JD.
Molecular Mass The protein has a predicted MW of 25.34 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Bis-Tris PAGE result.
Sl Sequence His22-Asn233
Solubility Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Appearance Lyophilized
Endotoxin Levels Less than 1 EU per μg by the LAL method.
Expression System HEK293
Gene Id A0A2K5WJ66
Amino Acid Sequence Recombinant Cynomolgus IL-10 R alpha Protein is expressed from HEK293 with His tag at the C-Terminus.It contains His22-Asn233.
Storage -20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Pdf View Document
Note The product is for research use only
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