Human IL-3 R Beta/CD131 Protein (IL3-HM2RB)
SKU: BTL-KB-P-02030 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | IL3-HM2RB |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human IL-3 R Beta/CD131 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Thr17-Trp443. |
| Target | IL-3 R Beta/CD131 |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | Interleukin-3 receptor (IL-3R) is a heterodimer that comprises an IL-3 specific alpha chain (IL-3R alpha) and a common beta chain (beta C) that is shared with the receptors for granulocyte-macrophage colony-stimulating factor (GM-CSF) and IL-5. The beta c subunit does not bind any cytokine by itself but is involved in the formation of high-affinity functional receptors for IL-5 and GM-CSF. These receptors belong to the cytokine receptor superfamily, but they are structurally and functionally more related to each other and thus make up a distinct subfamily. |
| Molecular Mass | The protein has a predicted MW of 74.63 kDa. Due to glycosylation, the protein migrates to 75-90 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Thr17-Trp443 |
| Appearance | Liquid |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | P32927-1 |
| Amino Acid Sequence | Recombinant Human IL-3 R Beta/CD131 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Thr17-Trp443. |
| Storage | Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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