Cynomolgus IL-7 R alpha/CD127 Protein (IL7-CM1RA)
SKU: BTL-KB-P-02058 |
Host: Cynomolgus |
Brand: Kactus Bio
Product Description
| Cat Number | IL7-CM1RA |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Cynomolgus IL-7 R alpha/CD127 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Glu21-Asp239. |
| Target | IL-7 R alpha/CD127 |
| Host | Cynomolgus |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | Interleukin 7 (IL-7) and its receptor (IL-7R, a heterodimer of IL-7Rα and γc) are essential for normal lymphoid development. IL-7 and IL-7R activate three main pathways: STAT5, PI3K/Akt/mTOR and MEK/Erk, ultimately leading to the promotion of leukemia cell viability, cell cycle progression and growth. |
| Molecular Mass | The protein has a predicted MW of 26.86 kDa. Due to glycosylation, the protein migrates to 45-55 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Glu21-Asp239 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | G7P7C5 |
| Amino Acid Sequence | Recombinant Cynomolgus IL-7 R alpha/CD127 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Glu21-Asp239. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | The product is for research use only |
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