Biotinylated Cynomolgus IL-18BP Protein (Primary Amine Labeling) (IL8-CM1BPB)
SKU: BTL-KB-P-02074 |
Host: Cynomolgus |
Brand: Kactus Bio
Product Description
| Cat Number | IL8-CM1BPB |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Biotinylated Cynomolgus IL-18BP Protein (Primary Amine Labeling) is expressed from HEK293 with His tag at the C-Terminus.It contains Thr28-Pro207. |
| Target | IL-18BP |
| Host | Cynomolgus |
| Purity | > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC |
| Scientific Background | Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggesting that IL-18 therapy could enhance anti-tumour immunity. IL-18BP, a high-affinity IL-18 decoy receptor, is frequently upregulated in diverse human and mouse tumours and limits the anti-tumour activity of IL-18 in mice. |
| Molecular Mass | The protein has a predicted MW of 21.14 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Thr28-Pro207 |
| Appearance | Liquid |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | A0A2K5UDJ4 |
| Amino Acid Sequence | Recombinant Biotinylated Cynomolgus IL-18BP Protein (Primary Amine Labeling) is expressed from HEK293 with His tag at the C-Terminus.It contains Thr28-Pro207. |
| Storage | Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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