Human IL-36 Beta/IL-1F8 Protein (ILB-HE036)
SKU: BTL-KB-P-02117 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | ILB-HE036 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human IL-36 Beta/IL-1F8 Protein is expressed from E.coli without tag.It contains Arg5-Glu157. |
| Target | IL-36 Beta/IL-1F8 |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | Within the IL-1 superfamily, IL-36 plays a pivotal role in both innate and adaptive immune responses. Of the four IL-36 isoforms, three have agonist activity (IL-36α, IL-36β, IL-36γ) and the fourth has antagonist activity (IL-36 receptor antagonist [IL-36Ra]). All IL-36 isoforms bind to the IL-36 receptor (IL-36R). Binding of IL-36α/β/γ to the IL-36R recruits the IL-1 receptor accessory protein (IL-1RAcP) and activates downstream signalling pathways mediated by nuclear transcription factor kappa B and mitogen-activated protein kinase signalling pathways. |
| Molecular Mass | The protein has a predicted MW of 17.23 kDa same as Bis-Tris PAGE result. |
| Sl Sequence | Arg5-Glu157 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | E.coli |
| Gene Id | Q9NZH7-2 |
| Amino Acid Sequence | Recombinant Human IL-36 Beta/IL-1F8 Protein is expressed from E.coli without tag.It contains Arg5-Glu157. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | The product is for research use only |
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